Drugs that target the GLP-1 and GIP pathways can suppress appetite, potentially ... | Hacker News

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		adamduren on May 20, 2023 \| parent \| context \| favorite \| on: Ozempic drug supresses desire to smoke, drink and ... Drugs that target the GLP-1 and GIP pathways can suppress appetite, potentially leading to a significant caloric deficit. This can lead to the body to break down muscle tissue to obtain protein for energy which could lead to a loss of lean muscle mass However, maintaining regular exercise and consuming sufficient protein can help to minimize the impact of lean muscle mass loss

sjtgraham on May 20, 2023 [–]

Protein is not what the body reaches for first in the absence of glucose/glycogen.

sn9 on May 21, 2023 | [–]

This is true but it's still extremely well established that you lose some muscle along with fat if you're in a prolonged caloric deficit without sufficient protein and strength training.

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